High-content cell imaging system CELENA X with monitor and researcher operating in laboratory environment | Logos Biosystems

CELL IMAGING

CELENA® X High Content Imaging System

Automated high content image acquisition and analysis for drug discovery and cell biology

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The CELENA® X High Content Imaging System is an integrated imaging system designed for rapid, high content image acquisition and analysis. Customizable imaging protocols, image-based and laser autofocusing modules, and a motorized XYZ stage simplify well plate imaging and slide scanning. The integrated CELENA® X Cell Analyzer software processes images and data for quantitative analysis. Analysis pipelines can be put together and reused to identify cellular or subcellular objects, process images for optimal data collection, and make various measurements. The CELENA® X is as flexible as it is powerful, with interchangeable objectives and filter cubes to accommodate a wide range of fixed and live cell imaging applications.

CELENA X high-content imaging system scanning multi-well plate for automated cell imaging
Fully Automated Plate And Slide Imaging
Automated vessel handling and scanning
Motorized XYZ stage, filter cube stage, and objective turret
CELENA X optical path diagram illustrating fluorescence and brightfield imaging technology
Laser Autofocus
Rapid and reproducible focusing
Minimized phototoxicity and photobleaching
Compact CELENA X high-content imaging system with touchscreen interface and modular design
Live Cell Assay Support
Onstage incubation system for a variety of experiments in physiological and non-physiological conditions
CELENA X fluorescence and brightfield cell images showing nuclei, morphology, and live cell assays
Four Imaging Modes
Fluorescence imaging in four channels, brightfield, color brightfield, and phase contrast imaging
CELENA X software interface for assay setup, image acquisition, and multi-well plate navigation
Powerful, Easy-To-Use User Interface
Simple setup of imaging protocols
Seamless integration of imaging and data analysis processes
CELENA X automated cell imaging results highlighting fluorescently stained cells for analysis
Customizable High Content Analysis
Create and customize image analysis projects
Quantitatively analyze multiple image-based phenotypes

Create Your Own Imaging And Analysis Workflows With The CELENA® X

Multi-well plate formats compatible with CELENA X for high-throughput imaging

Imaging

Raw images
Metadata
Cell culture flask imaging using CELENA X for real-time monitoring

Image Analysis

Morphology of individual cells and organelles
Spatial distribution of targets
Multiple measurements per cell
Differentiation of multiple phenotypes
Assay kit integration with CELENA X for diverse cell-based experiments

Data Analysis

Analyzed images
Result files
Graphs (coming soon)
       

Abundant Applications

The CELENA® X Cell Analyzer software is incredibly powerful and its ability to batch process makes it ideal for high content analysis. The powerful and flexible software allows for the creation and customization of workflows that can be used for the simplest fixed cell assays to more complicated, time-lapse live cell assays.

Versatile And Customizable For Your Cell Imaging Needs

Image of a vessel holder plate for accommodating flasks, dishes, plates, and slides in the CELENA cell imaging system

Vessel Holder Selection Guide

A collection of vessel holders are available to accommodate various flasks, dishes, plates, and slides.
Image of Olympus microscope objectives recommended for the CELENA cell imaging system
Vessel Holder Selection Guide
Image of three LED filter cubes in different colors for fluorescence imaging with the CELENA cell imaging system

Objective Selection Guide

Download our objective selection guide to see the Olympus objectives we recommend for the CELENA® X.
Objective Selection Guide

LED Filter Cube Selection Guide

Download our LED filter cube selection guide to find which filter cubes fit your needs the best.
LED Filter Cube Selection Guide

Why Scientists Love CELENA® Cell Imagers

Testimonials

(5.0)
Peter Davis

Great to use, inexpensive - watch out big microscopy companies...
The Celena-X is so easy to use, it has huge flexibility and it is oh so affordable making the 'big name brands' look like a rip off!

ATA Scientific

(5.0)
David Benz

Perfect combination of high content and high quality imaging.
The speed of image acquisition is outstanding and the images generated are of high quality. Together with the easy-to-use software, it is a great product.

Institut für Zellbiologie und Immunologie Stuttgart

Read Peer Reviews

Where The CELENA® X Has Been Cited

Citations

Primary cilia and the reciprocal activation of AKT and SMAD2/3 regulate stretch-induced autophagy in trabecular meshwork cells.

2021. Shim MS, Nettesheim A, Dixon A, Liton PB. Proceedings of the National Academy of Sciences of the United States of America 118(13):e2021942118.

Cathepsin B Localizes in the Caveolae and Participates in the Proteolytic Cascade in Trabecular Meshwork Cells. Potential New Drug Target for the Treatment of Glaucoma.

2021. Nettesheim A, Shim MS, Dixon A, Raychaudhuri U, Gong H, Liton PB. Journal of Clinical Medicine 10(1):78.

Indirubin-3'-monoxime induces paraptosis in MDA-MB-231 breast cancer cells by transmitting Ca 2+ from endoplasmic reticulum to mitochondria.

2021. Dilshara MG, Neelaka Molagoda IM, Prasad Tharanga Jayasooriya RG, Choi YH, Park C, Kim GY. Archives of Biochemistry and Biophysics 698:108723.

Revascularization and limb salvage following critical limb ischemia by nanoceria-induced Ref-1/APE1-dependent angiogenesis.

2020. Park IS, Mahapatra C, Park JS, Dashnyam K, Kim JW, Ahn JC, Chung PS, Yoon DS, Mandakhbayar N, Singh RK, Lee JH, Leong KW, Kim HW. Biomaterials 242:119919.

Synthesis and Properties of CurNQ for the Theranostic Application in Ovarian Cancer Intervention.

2020. Freidus LG, Kumar P, Marimuthu T, Pradeep P, Pillay V, Choonara YE. Molecules (Basel, Switzerland) 25(19):4471.

View Cited Works

Resources

Downloads

CELENA® X
Brochure

2022-04-07 | 2 MB

Download
CELENA®X vessel holder dimension
Selection Guide

2021-07-01 | 282.34 KB

Download
CELENA®X High Content Imaging System
Installation Guide

2021-06-18 | 665.56 KB

Download
CELENA®X
Quick Start Guide

2019-10-30 | 901.13 KB

Download
Ordering Information
Cat # Product Qty
CX30000 CELENA® X High Content Imaging System 1 unit
I10530 CX Stage Top Incubator, Basic [Tokai] 1 set
I10531 CX Stage Top Incubator, Pro [Tokai] 1 set
I10500 Heating System for Multi-well Plates [Ibidi] 1 set
I10502 Gas Incubation System for CO2 [Ibidi] 1 set
I10503 Gas Incubation System for CO2/O2 [Ibidi] 1 set
I10030 UPLFLN 4X, Olympus 1 unit
I10031 UPLFLN 10X2, Olympus 1 unit
I10036 LUCPLFLN 20X2, Olympus 1 unit
I10037 LUCPLFLN 40X2, Olympus 1 unit
I10038 UPLFLN 4XPH, Olympus 1 unit
I10039 UPLFLN 10X2PH, Olympus 1 unit
I10044 LUCPLFLN 20XPH2, Olympus 1 unit
I10045 LUCPLFLN 40XPH2, Olympus 1 unit
I10046 PLAPON 1.25X, Olympus 1 unit
I10047 PLAPON 2X, Olympus 1 unit
I10052 UPLXAPO 60XO, Olympus 1 unit
I10051 UPLXAPO 100XO, Olympus 1 unit
I10130 DAPI (Ex395/25, Em460/50) 1 unit
I10131 EGFP (Ex470/30, Em530/50) 1 unit
I10132 RFP (Ex530/40, Em605/55) 1 unit
I10133 mCherry (Ex580/25, Em645/75) 1 unit
I10134 ECFP (Ex436/20, Em480/40) 1 unit
I10135 EYFP (Ex500/20, Em535/30) 1 unit
I10136 DSRed (Ex530/40, Em620/60) 1 unit
I10137 Cy5 (Ex620/60, Em700/75) 1 unit
I10138 Cy7 (Ex710/75, Em810/90) 1 unit
I10139 Cy3/TRITC Long Pass (Ex530/40, Em570lp) 1 unit
I10140 GFP Long Pass (Ex470/40, Em500lp) 1 unit
I10141 Cy5 Long Pass (Ex620/60, Em665lp) 1 unit
I10142 Custom Filters 1 unit
I10410 Joystick 1 unit

 

Specifications
Supported labware Slides, multi-well plates (6 to 1536 wells), petri dishes, culture flasks
Imaging modes 4-channel fluorescence, brightfield, phase contrast, color brightfield
Light source High-power LED filter cubes with adjustable intensity (>50,000 hours per filter cube)
Filter cube stage Motorized; 4 interchangeable fluorescence filter cubes and 1 brightfield filter cube
Available filters DAPI, EGFP, RFP, mCherry, ECFP, EYFP, DSRed, Cy5, Cy7, Cy3/TRITC Long Pass, GFP Long Pass, Cy5 Long Pass, custom filters
Objective turret Motorized; 5 interchangeable objectives
Compatible objectives 1.25-100X; Olympus, Zeiss, and Logos Biosystems objectives
Condenser Motorized; basic or phase contrast
Basic: 60 mm LWD condenser, 4 positions
Phase contrast: 60 mm LWD condenser, 4 positions with 3 phase annuli
Camera Monochrome: CMOS, 1.92 MP
(optional) Color: CMOS, 1.92 MP
Image outputs Monochrome: 16‐bit (12‐bit dynamic range) TIF, PNG, or JPG
Color: 24-bit color TIF, PNG, or JPG
Movies: MP4
Autofocus method Image-based autofocus
(optional) Laser autofocus
Stage Motorized X/Y-stage (120 mm x 80 mm); motorized Z-stage (10 mm)
Stage control CELENA® X Explorer
(optional) Joystick
Computer External PC
Monitor 27” 4K UHD monitor
Software User interface: CELENA® X Explorer
Analysis: CELENA® X Cell Analyzer
Power 100-240 VAC, 250 W, 50/60 Hz
Dimensions Main body: 39 x 46 x 50 cm (15.4 x 18.1 x 19.7 in)
Controller: 17 x 30 x 23 cm (6.7 x 11.8 x 9.1 in)
Weight Main body: 33 kg (72.8 lbs)
Controller: 7 kg (15.4 lbs)