X-CLARITY™ Hydrogel Solution Kit – Logos Biosystems | Advanced Imaging Solutions for Research Excellence

X-CLARITY™ Hydrogel Solution Kit

The X-CLARITY™ Hydrogel Solution Kit is a pre-tested hydrogel solution for uniform and consistent tissue-hydrogel hybridization. The kit is composed of the X-CLARITY™ Hydrogel Solution and the X-CLARITY™ Polymerization Initiator.
X-CLARITY™ Hydrogel Solution is an acrylamide-based solution used to create polyacrylamide, a chemically inert and electrically neutral gel matrix. The X-CLARITY™ Hydrogel Solution contains no bis-acrylamide or paraformaldehyde.

The X-CLARITY™ Polymerization Initiator is a thermal free radical initiator also known as VA-044. VA-044 is relatively stable at room temperature but undergoes rapid hemolytic decomposition when heated in aqueous solution, releasing cationic free radicals that initiate the polymerization of hydrogel monomers

Compatible Instruments

X-CLARITY™ Tissue Clearing System

References
1. Lee, E et al. ACT-PRESTO: Rapid and consistent tissue clearing and labeling method for 3 dimensional (3D) imaging. Sci Rep 6, 18631 (2016)
2. Yang, B. et al. Single-cell phenotyping within transparent intact tissue through whole-body clearing. Cell 158, 945–958 (2014)
3. Chung, K. et al. Structural and molecular interrogation of intact biological systems. Nature 497, 332–337 (2013)

Specifications

X-CLARITY^TM Hydrogel Solution
Product identity	4% acrylamide solution
Molecular formula	C₃H₅NO
Molecular weight	71.08 g/mol
Appearance	Clear liquid
Storage	4°C in the dark
X-CLARITY^TM Polymerization Initiator
Molecular formula	C₁₂H₂₂N₆· 2HCl
Molecular weight	323.33 g/mol
Appearance	Pale yellow powder
10-hour half-life	44°C (in water)
Storage	4°C

Ordering Information

Cat #	Description	Qty
C1310X	X-CLARITY™ Hydrogel Solution Kit	1 box
	– X-CLARITY™ Hydrogel Solution (1 L)
	– X-CLARITY™ Polymerization Initiator (2.5 g)
C13103	X-CLARITY™ Hydrogel Solution	1 L
C13104	X-CLARITY™ Polymerization Initiator	2.5 g