X-CLARITY is the definitive solution for an effective, robust and highly repeatable clearing. X-CLARITY helps clearing expert users to have more reproducible and standardized data, opening the possibility to have robust quantitative data even from cleared tissue samples, as well as dummies that look out this technique for the first time. In our facility very often people who had never even been done just simple immunofluorescences they were able to get perfect cleared samples for imaging (confocal or two-photon).